Passend zu meinem Post über Casey Luskin und seine Behauptung, dass Wissenschaftler ohne ID nie auf die Idee gekommen wären, nach Funktionen in non-coding DNA zu schauen, ist jetzt dieser Artikel in Nature erschienen, dessen Autoren das nun vollständig sequenzierte Opossum-Genom unter anderem nach konservierten nicht-codierenden Elementen durchsucht haben:Mikkelsen et al., Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature 447, 167-177 (10 May 2007)
The Loom hat ein hervorragendes Post zu dem Thema. Als Appetizer:
But the opossum is also interesting for what it tells us about our evolutionary history. If we examine the genome of a monkey or a horse or a dog, we're still looking relatively close relatives. Like us, each of them is yet another variation on the placental mammal. We all share an ancestor that already had a placenta and a lot of other biological features. Until today, we had to travel very far beyond placental mammals to find another relative whose genome has been sequenced: the chicken. The common ancestor of chickens and us was a cold-blooded reptile-like creature that lived 300 million years ago. So the opossum falls nicely right in the middle of that gap.MfG,
Once the opossum team sequenced the raw code of the genome they began to dissect it. They counted up 18,648 genes (remarkably close to our own total at the moment). They matched opossum genes to related versions in placental mammals, and also looked at the parts of the genome that don't encode proteins. They looked at the chromosomes of opossums as well. Over time, giant chunks of mammal chromosomes also get flipped in reverse, and by comparing the opossum genome to other mammal genomes, scientists can reconstruct the overall look of the chromosomes of our common ancestor some 180 million years ago.
JLT
[edit]Uncommon Descent hat auch was zum Opossum-Genom zu sagen. Offensichtlich bekommen sie dabei einiges nicht so ganz auf die Reihe, siehe Denialism blog.[/edit]
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