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Anders als bisher angenommen, ist das Muster der Genaktivierung, das bei Tetrapoden zur Ausbildung von Gliedmaßen während der Embryonalentwicklung führt, ein sehr primitives Merkmal, d. h. schon bei den Stören zu finden. Bisher hatte man angenommen, dass dieses Muster eine "Neuentwicklung" der Tetrapoden war, da Zebrafische, die als Modellorganismen verwendet werden, dieses Muster nicht aufweisen. Jetzt zeigt es sich, dass "moderne" Fische (wie Zebrafische) diese Art der Genaktivierung offenbar erst sekundär "verloren" haben.
Tetrapods have a second phase of Hox gene expression that happens later in development. During this second phase, hands and feet develop. Although this second phase is not known in zebrafish, the scientists found that it is present in paddlefish, which reveals that a pattern of gene activity long thought to be unique to vertebrates with hands and feet is in fact much more primitive.[Quelle: New genetic data overturn long-held theory of limb development. The University of Chicago Press Release]
This is the first molecular support for the theory that the genes to help make fingers and toes have been around for a long time—well before the 375-million-year-old Tiktaalik roseae, the newly found species discovered in 2004 by Shubin and colleagues. Tiktaalik provided a missing evolutionary link between fish and tetrapods and was among the first creatures that walked out of water onto land.
Prior to this find, scientists had little evidence of where the wrist came from. A popular theory, one Shubin himself subscribed to, was that it was a novel development—that genetic variance gave rise to an entirely new function.
What Tiktaalik revealed morphologically, Shubin, Davis and Dahn have proven genetically.
Mehr zu dem Thema gibt's von Carl Zimmer [The Loom], wie immer ein sehr guter Artikel.
MfG,
JLT
[Bild-Quelle: Wikipedia]
Dies ist mein 150stes Post! Kaum zu glauben...
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